2026年4月17日

A hidden cause of dull skin and premature aging

A blood sugar spike refers to a rapid rise in blood glucose levels after consuming carbohydrates, followed by a sharp drop due to insulin activity.

These abrupt fluctuations can trigger oxidative stress and inflammation in the body, promoting glycation and the formation of advanced glycation end products (AGEs). This process ultimately contributes to reduced skin elasticity and a dull complexion.

Brownlee, M. “Advanced protein glycosylation in diabetes and aging.” Annu Rev Med. 1995;46:223–234.

AGEs are substances formed when excess glucose binds to proteins in the body. When AGEs accumulate in collagen and elastin, they cause these structural proteins to stiffen—leading to wrinkles, sagging, and loss of elasticity.

AGEs also have a yellowish-brown characteristic. As they build up, they can cause overall skin discoloration and dullness. Combined with UV exposure and stress, they accelerate the appearance of an “aged” face.

Gkogkolou, P., Böhm, M. “Advanced glycation end products: Key players in skin aging?” Dermatoendocrinol. 2012;4(3):259–270.

3 blood sugar control habits for better skin:

1) Change the order of what you eat

Start with vegetables, followed by protein, then carbohydrates. This helps slow the rise in blood sugar.

2) Choose less refined carbohydrates

Replace white rice and white bread with brown rice, whole grain bread, or mixed grains to help prevent spikes.

3) Make light post-meal activity a habit

A 10–15 minute walk or taking the stairs promotes glucose uptake into muscles and helps stabilize blood sugar levels.

Colberg, S. R., et al. “Exercise and glycemic control after meals in type 2 diabetes.” Diabetes Care. 2009;32(11):2109–2111.

Just like afternoon drowsiness, skin aging is strongly influenced by blood sugar levels.

Why not start with your very next meal? Small changes in daily habits can lead to “inside-out” anti-aging.